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Inferring Personalized Cell-Cell Communication Networks in Colorectal Cancer with Individualized Causal Discovery

2025-09-22

Abstract excerpt

Understanding tumor heterogeneity at the resolution of individualized cell–cell communication networks (CCCNs) remains a major computational challenge in precision oncology. Existing inference methods largely rely on population-level correlation and thus fail to capture patient-specific signaling patterns across diverse cell types. To address this limitation, we developed an integrative computational framework com...

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Literature Corpus work
6a7cce66-0995-5842-8daa-d443ea387b06
DOI
10.1101/2025.09.20.677543
Open publication

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Inferring Personalized Cell-Cell Communication Networks in Colorectal Cancer with Individualized Causal DiscoveryDOI 10.1101/2025.09.20.677543
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