Article

Cell-CLIP: Multi-algorithm causal discovery of directed cell program interaction networks from single-cell transcriptomics

2025-12-03

Abstract excerpt

Cell-cell communication networks govern tissue function in health and disease, yet existing computational tools rely on static ligand–receptor databases or correlation-based analyses that cannot distinguish direct causal relationships from confounded or indirect associations. We introduce Cell-CLIP (Cellular Causal Learning and Inference Pipeline), a modular framework that combines (i) mask-aware patient-level JAS...

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Literature Corpus work: 82300f4d-8b95-5014-84e8-8c836d816aaf
DOI: 10.64898/2025.12.01.691666

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