Article

Bioinformatics-based stereochemical elucidation of MM 46115: an unusual antiviral spirotetronate that inhibits clathrin-mediated endocytosis

2025-09-18

Abstract excerpt

<h4>Summary</h4> The influenza virus is a leading cause of respiratory tract infection in humans, with the emergence of antiviral drug resistance posing an ongoing challenge to the treatment of influenza. This underscores the urgent need for effective new antiviral treatments. Spirotetronates are a family of bacterial natural products with a range of potent bioactivities. Some members of this family have antivira...

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Literature Corpus work: 6a700635-c1a5-5780-bebb-b05768bbf1b5
DOI: 10.1101/2025.09.18.677008

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Bioinformatics-based stereochemical elucidation of MM 46115: an unusual antiviral spirotetronate that inhibits clathrin-mediated endocytosisDOI 10.1101/2025.09.18.677008Read

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