Article

CVD-associated SNPs with regulatory potential drive pathologic non-coding RNA expression

2023-02-12

Abstract excerpt

<h4>Background</h4> Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Genome-wide association studies (GWAS) have identified many single nucleotide polymorphisms (SNPs) appearing in non-coding genomic regions in CVDs. The SNPs may alter gene expression by modifying transcription factor (TF) binding sites and lead to functional consequences in cardiovascular traits or diseases. To understand...

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Literature Corpus work: 6a11f898-7ee5-5460-bdcd-e38c05d07c93
DOI: 10.1101/2023.02.12.528184

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