Article

CVD-associated SNPs with regulatory potential drive pathologic non-coding RNA expression

2023-03-01

Abstract excerpt

<h4>Background: </h4> Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Genome-wide association studies (GWAS) have identified many single nucleotide polymorphisms (SNPs) appearing in non-coding genomic regions in CVDs. The SNPs may alter gene expression by modifying transcription factor (TF) binding sites and lead to functional consequences in cardiovascular traits or diseases. To understan...

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Literature Corpus work: 5c527f5c-2252-54c9-a584-b769e25e0eaf
DOI: 10.21203/rs.3.rs-2629198/v1

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