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Article

CVD-associated SNPs with regulatory potential reveal novel non-coding disease genes.

Human genomics - 25 Jul 2023

Zhu Chaonan, Baumgarten Nina, Wu Meiqian, Wang Yue, Das Arka Provo, Kaur Jaskiran, Ardakani Fatemeh Behjati, Duong Thanh Thuy, Pham Minh Duc, Duda Maria, Dimmeler Stefanie, Yuan Ting, Schulz Marcel H, Krishnan Jaya

Abstract excerpt

BACKGROUND: Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Genome-wide association studies (GWAS) have identified many single nucleotide polymorphisms (SNPs) appearing in non-coding genomic regions in CVDs. The SNPs may alter gene expression by modifying transcription factor (TF) binding sites and lead to functional consequences in cardiovascular traits or diseases. To understand the...

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PMID: 37491351
DOI: 10.1186/s40246-023-00513-4
PMCID: PMC10369730

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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