Article

A de novo paradigm for male infertility

2021-03-22

Abstract excerpt

<title>Abstract</title> <p>De novo mutations (DNMs) are known to play a prominent role in many sporadic disorders with reduced fitness. We hypothesize that DNMs play an important role in male infertility and explain a significant fraction of the genetic causes of this understudied disorder. We performed a trio-based exome-sequencing study in a unique cohort of 185 infertile males and their unaffected parents. Fol...

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Literature Corpus work: 69fbc704-adb8-5135-9b79-3699e51d4b73
DOI: 10.21203/rs.3.rs-332732/v1

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