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Article

Sequence analysis of 37 candidate genes for male infertility: challenges in variant assessment and validating genes

3 Sept 2019

Abstract excerpt

BACKGROUND: The routine genetic analysis for diagnosing male infertility has not changed over the last twenty years, and currently available tests can only determine the etiology of 4% of unselected infertile patients. Thus, to create new diagnostic assays, we must better understand the molecular and genetic mechanisms of male infertility. Although next-generation sequencing allows for simultaneous analysis of...

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PMID: 31479588
DOI: 10.1111/andr.12704

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