Article

Biallelic mutations in <i>M1AP</i> are a frequent cause of meiotic arrest leading to male infertility

2019-10-15

Abstract excerpt

Male infertility affects ∼7% of men in Western societies, but its causes remain poorly understood. The most clinically severe form of male infertility is non-obstructive azoospermia (NOA), which is, in part, caused by an arrest at meiosis, but so far only few genes have been reported to cause germ cell arrest in males. To address this gap, whole exome sequencing was performed in 60 German men with complete meiotic...

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Literature Corpus work: 59a5dc88-710c-5534-8e2e-d59bd572abfa
DOI: 10.1101/803346

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