Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The genetic insights of sporadic male infertility: a systematic review of WES and WGS studies (2014-2024).

Human genomics - 25 May 2026

Zahi Hoda, Sfifou Fatima, Slaoui Meriem, Chentoufi Lamyae, Abouqal Redouane, Hardizi Houyam

Abstract excerpt

Male infertility is a complex and heterogeneous disorder. It has a significant genetic component, although some cases remain idiopathic. Next-generation sequencing, particularly whole-exome (WES) and whole-genome sequencing (WGS) has become a powerful tool for uncovering new genetic causes. This systematic review aimed to identify and synthesize genes linked to male infertility reported in WES or WGS studies. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Azoospermia
Share to Exome Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Infertility, Male

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 42186055
DOI: 10.1186/s40246-026-00991-2
PMCID: PMC13386772

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The genetic insights of sporadic male infertility: a systematic review of WES and WGS studies (2014-2024).PMID 42186055Read ↗

Point-of-care whole-exome sequencing of idiopathic male infertility.Semantic proximity Read ↗

How exome sequencing improves the diagnostics and management of men with non‐syndromic infertilitySemantic proximity Read ↗

Genetics of Male Infertility – Present and FutureSemantic proximity Read ↗

Toward clinical exomes in diagnostics and management of male infertility.Semantic proximity Read ↗

Identification of deleterious variants in patients with male infertility due to idiopathic non-obstructive azoospermiaSemantic proximity Read ↗

Genetic Testing for Monogenic Forms of Male Infertility Contributes to the Clinical Diagnosis of Men with Severe Idiopathic Male InfertilitySemantic proximity Read ↗

A systematic review and standardized clinical validity assessment of male infertility genesSemantic proximity Read ↗

A systematic review and evidence assessment of monogenic gene-disease relationships in human female infertility and differences in sex development.Semantic proximity Read ↗

Syndromic male subfertility: A network view of genome-phenome associations.Semantic proximity Read ↗

Actionable secondary findings following exome sequencing of 836 non-obstructive azoospermia cases and their value in patient managementSemantic proximity Read ↗

Contemporary genetics-based diagnostics of male infertilitySemantic proximity Read ↗

Mate-pair genome sequencing reveals structural variants for idiopathic male infertilitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.