Article

Crosstalk between CD8 <sup>+</sup> T cells and systemic bile acid metabolism controls LCMV-induced immunopathology

2025-08-17

Abstract excerpt

Antiviral immunity has a profound effect on host metabolism, which can, in turn, modulate immune responses and influences disease pathology. Among its many functions, the liver orchestrates systemic bile acid (BA) metabolism, a pathway disrupted in chronic liver diseases such as viral hepatitis. BAs have become increasingly recognized for their immunomodulatory properties, and multiple BA species are being explore...

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Literature Corpus work: 69fb796b-2458-59b1-b2f3-0c7a3d521d04
DOI: 10.1101/2025.08.17.670599

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