Article

Mechanisms and Clinical Significance of Bile Acid Metabolism Reprogramming in Hepatocellular Carcinoma Immunotherapy Response

2026-02-17

Abstract excerpt

<title>Abstract</title> <p>Background Hepatocellular carcinoma (HCC) constitutes the foremost cause of cancer-related mortality globally, and patients exhibit significant variations in their response to immunotherapy. Recent research has shown that elevated bile acids (BAs) are closely associated with HCC. Methods We collected surgical tumor samples from six HCC patients and categorized them into recurrence (FA...

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Literature Corpus work: 15eda08c-60d3-50df-8d1d-9572d0a0d599
DOI: 10.21203/rs.3.rs-8649754/v1

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