Article

Intestinal stem cell renewal controlled by capillary morphogenesis gene 2 following injury

2025-01-08

Abstract excerpt

<h4>SUMMARY</h4> Patients with the rare genetic disorder Hyaline Fibromatosis Syndrome (HFS) often succumb before 18 months of age due to severe diarrhea and protein-losing enteropathy. As HFS is caused by loss-of-function mutations in the gene encoding capillary morphogenesis gene 2 (CMG2), also known as Anthrax Toxin Receptor 2, these symptoms highlight a critical yet unclear role for CMG2 in the gut. Here, we...

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Literature Corpus work: 69d16d7a-8c25-55cc-bbb6-0173bc9bb3b6
DOI: 10.1101/2025.01.07.631493

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