Article

Genome-wide association study of REM-sleep behaviour disorder identifies new risk loci

2025-12-02

Abstract excerpt

Rapid-eye-movement (REM)-sleep behaviour disorder (RBD) can be a prodromal stage of α-synucleinopathies, including Parkinson’s disease (PD) and dementia with Lewy bodies (DLB), and provides a unique opportunity to study and understand early neurodegeneration. Previous research on RBD has identified common risk loci in several PD and DLB genes, but the full extent of its genetic architecture and disease-specific as...

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Literature Corpus work: 698dd5ad-de4e-5c29-a633-00822478d4cc
DOI: 10.64898/2025.12.01.25339623

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