Article

Efficient and reliable measles reprogramming platform for the generation of human iPSC

2025-10-12

Abstract excerpt

We previously established the Measles virus (MeV) vector for reprogramming somatic cells into induced pluripotent stem cells (iPSCs); however, efficiency was limited to 0.2%. Here, we present the next generation that reprograms with an average efficiency of up to 2.3% and with similar or superior efficiency to the Sendai system. Twenty of the ninety iPSC isolated clones were amplified and analyzed. All clones show...

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Literature Corpus work: 6989b38f-bb4b-5b50-96de-0e53842b904b
DOI: 10.1101/2025.10.10.677451

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