Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of MERRF patient-derived induced pluripotent stem cell line iMERRF-C7.

Stem cell research - 1 Nov 2016

Liang Dong, Hu Huanran, Xu Tianhui, Wang Yan, Hu Ping, Xu Zhengfeng

Abstract excerpt

Human iPSC line iMERRF-C7 was generated from PBMCs of a patient with mitochondrial disorder MERRF. Using Sendai virus, the reprogramming factors Oct3/4, Sox2, Klf4, and cMyc were delivered non-integratively. The resulting iPSCs expressed pluripotency markers, could differentiate into the three germ layers in vivo, had normal genomic structure, and retained the disease-causing m.8344 mutation with similar...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cellular Reprogramming
Share to Karyotype
Share to Kruppel-Like Factor 4

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MERRF Syndrome

Share to Mice, Inbred NOD

Share to Mice, SCID

Share to Sendai virus

Share to Teratoma

Source

Identifiers

PMID: 27934592
DOI: 10.1016/j.scr.2016.11.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of MERRF patient-derived induced pluripotent stem cell line iMERRF-C7.PMID 27934592Read ↗

Generation of an induced pluripotent stem cell (iPSC) line from a 40-year-old patient with the A8344G mutation of mitochondrial DNA and MERRF (myoclonic epilepsy with ragged red fibers) syndrome.Semantic proximity Read ↗

Generation of a human induced pluripotent stem cell (iPSC) line (IBMS-iPSC-057-05) from a patient with familial parkinsonism and polyneuropathy having a heterozygous p.Y314S mutation in UQCRC1 gene.Semantic proximity Read ↗

Reprogramming of two induced pluripotent stem cell clones from a patient with a novel MT-ATP6/8 mutation (m.8570 T > C).Semantic proximity Read ↗

RNA-based generation of iPSCs from a boy carrying the mutation m.9185 T>C in the mitochondrial gene MT-ATP6 and from his healthy mother.Semantic proximity Read ↗

Characterization of two iPSC lines from patients with maternally inherited leigh (MILS) and neuropathy, ataxia, and retinitis pigmentosa (NARP) syndrome carrying the MT-ATP6 m.8993 T>G mutation at different degrees of heteroplasmy.Semantic proximity Read ↗

Generation of the human induced pluripotent stem cell line PUMCi005-A from a patient with Perrault syndrome.Semantic proximity Read ↗

Generation of two iPSC lines (FAMRCi006-A and FAMRCi006-B) from patient with dilated cardiomyopathy and Emery-Dreifuss muscular dystrophy associated with genetic variant LMNAp.Arg527Pro.Semantic proximity Read ↗

The human induced pluripotent stem cell line CTGUi-002A was generated from a Perrault syndrome patient.Semantic proximity Read ↗

Generation of two isogenic human induced pluripotent stem cell lines from a 15 year-old female patient with MERRF syndrome and A8344G mutation of mitochondrial DNA.Semantic proximity Read ↗

Generation of four iPSC lines from four patients with Leigh syndrome carrying homoplasmic mutations m.8993T > G or m.8993T > C in the mitochondrial gene MT-ATP6.Semantic proximity Read ↗

Generation of a human iPSC line (MPIi008-A) from a patient with Denys-Drash syndrome.Semantic proximity Read ↗

Establishment of EHMT1 mutant induced pluripotent stem cell (iPSC) line from a 11-year-old Kleefstra syndrome (KS) patient with autism and normal intellectual performance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.