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Sendai virus persistence questions the transient naive reprogramming method for iPSC generation

2024-03-12

Abstract excerpt

Since the revolutionary discovery of induced pluripotent stem cells (iPSCs) by Shinya Yamanaka, the comparison between iPSCs and embryonic stem cells (ESCs) has revealed significant differences in their epigenetic states and developmental potential. A recent compelling study published in Nature by Buckberry et al. 1 demonstrated that a transient-naive-treatment (TNT) could facilitate epigenetic reprogramming and...

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Literature Corpus work: 2eca2b5d-8c8b-5c36-8f8b-e2504af5b04d
DOI: 10.1101/2024.03.07.583804

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