Article

Lupus disease flares are concordant with immune responses to blooms of lipoglycan-expressing <i>Ruminococcus blautia gnavus</i> strains arising from unstable gut microbiota communities

2022-06-29

Abstract excerpt

Whereas genetic susceptibility for Systemic Lupus Erythematosus has been well explored, the precipitants for clinical disease flares remain a mystery. To investigate for dynamic-relationships between gut-microbial communities and Lupus disease activity, we performed taxonomic surveys of fecal 16S rRNA gene amplicon-libraries from Lupus patients and healthy volunteers, obtained at serial timepoints over many months...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 69867f2d-aa24-528a-8d0c-055020e023e1
DOI: 10.1101/2022.06.28.498027

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Lupus disease flares are concordant with immune responses to blooms of lipoglycan-expressing <i>Ruminococcus blautia gnavus</i> strains arising from unstable gut microbiota communitiesDOI 10.1101/2022.06.28.498027Read

Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flaresSemantic proximity Read

Lupus nephritis is linked to disease-activity associated expansions and immunity to a gut commensalSemantic proximity Read

Recent Advances in Our Understanding of the Link between the Intestinal Microbiota and Systemic Lupus ErythematosusSemantic proximity Read

Pathogenic strains of a gut commensal drive systemic platelet activation and thromboinflammation in lupus nephritisSemantic proximity Read

Outgrowth of Escherichia is susceptible to aggravation of systemic lupus erythematosusSemantic proximity Read

Fecal Microbiota Changes in NZB/W F1 Mice After Induction of Lupus DiseaseSemantic proximity Read

Gut microbiota in systemic lupus erythematosus patients and lupus mouse model: a cross species comparative analysis for biomarker discoverySemantic proximity Read

An Autoimmunogenic and Proinflammatory Profile Defined by the Gut Microbiota of Patients With Untreated Systemic Lupus Erythematosus.Semantic proximity Read

Intestinal Dysbiosis Associated with Systemic Lupus ErythematosusSemantic proximity Read

Fungal microbiome in gut of systemic lupus erythematosus (SLE)-prone mice (pristane and FCGRIIb deficiency), a possible impact of fungi in lupusSemantic proximity Read

Dynamics of Gut Microbiota in Autoimmune LupusSemantic proximity Read

A Link Between Plasma Microbial Translocation, Microbiome, and Autoantibody Development in First‐Degree Relatives of Systemic Lupus Erythematosus PatientsSemantic proximity Read