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Longitudinal gut microbiome analyses and blooms of pathogenic strains during lupus disease flares

27 Jun 2023

Abstract excerpt

OBJECTIVE: Whereas genetic susceptibility for systemic lupus erythematosus (SLE) has been well explored, the triggers for clinical disease flares remain elusive. To investigate relationships between microbiota community resilience and disease activity, we performed the first longitudinal analyses of lupus gut-microbiota communities. METHODS: In an observational study, taxononomic analyses, including multivariate...

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PMID: 37365013
DOI: 10.1136/ard-2023-223929

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