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Article

Lupus nephritis is linked to disease-activity associated expansions and immunity to a gut commensal

19 Feb 2019

Abstract excerpt

Background/Purpose To search for a transmissible agent involved in lupus pathogenesis, we investigated the faecal microbiota of patients with systemic lupus erythematosus (SLE) for candidate pathobiont(s) and evaluated them for special relationships with host immunity. Methods In a cross-sectional discovery cohort, matched blood and faecal samples from 61 female patients with SLE were obtained. Faecal 16 S rRNA...

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PMID: 30782585
DOI: 10.1136/annrheumdis-2018-214856

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