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Article

From Adult Stem Cells to Cancer Stem Cells

2006-11-01

Abstract excerpt

Abstract: Carcinogenesis is characterized by “initiation,”“promotion,” and “progression” phases. The “stem cell theory” and “de‐differentiation” theories are used to explain the origin of cancer. Growth control for stem cells, which lack functional gap junctional intercellular communication (GJIC), involves negative soluble or niche factors, while for progenitor cells, it involves GJIC. Tumor promoters, hormones ,...

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Literature Corpus work
698362ce-f536-5ca9-99ba-205d84a21d22
DOI
10.1196/annals.1386.018
Open publication

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