Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ontogeny, pathology, oncology.

The International journal of developmental biology - 1 Mar 1993

Papaioannou V E

Abstract excerpt

This article traces the history of using embryo-derived stem cells for genetic manipulation--first teratocarcinoma stem cells and then embryonic stem cells. It encompasses several decades of research investigating the similarity between cellular mechanisms of normal growth and differentiation in the embryo and abnormal growth and differentiation in neoplasia. The limited developmental potential of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Germ Cells
Share to History, 20th Century

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Neoplastic Stem Cells

Share to Oncogenes

Share to Teratoma

Source

Identifiers

PMID: 8507567

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ontogeny, pathology, oncology.PMID 8507567Read ↗

Teratocarcinoma: neoplastic lessons about normal embryogenesisSemantic proximity Read ↗

Investigation of early neoplastic transformation and premalignant biology using genetically engineered organoid modelsSemantic proximity Read ↗

Stem cells and somatic cells: reprogramming and plasticity.Semantic proximity Read ↗

From shape-shifting embryonic cells to oncology: The fascinating history of epithelial mesenchymal transitionSemantic proximity Read ↗

The plasticity of germ cell cancers and its dependence on the cellular microenvironmentSemantic proximity Read ↗

Cancers make their own luck: theories of cancer origins.Semantic proximity Read ↗

Echoes of the embryo: using the developmental biology toolkit to study cancer.Semantic proximity Read ↗

Review Paper: Cancer Stem Cells and Cancer Nonstem Cells: From Adult Stem Cells or from Reprogramming of Differentiated Somatic CellsSemantic proximity Read ↗

A polyomavirus-positive Merkel cell carcinoma mouse model supports a unified cancer originSemantic proximity Read ↗

The evolution of cancer modeling: the shadow of stem cells.Semantic proximity Read ↗

Morphogenesis and cancer.Semantic proximity Read ↗

Yolk sac tumours revisited. A review of their many faces and namesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.