Article

A <i>Clostridia</i> -rich microbiota contributes to increased excretion of bile acids in diarrhea-predominant irritable bowel syndrome

2019-05-12

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> An excess of fecal bile acids (BAs) is thought to be one of the mechanisms for diarrhea-predominant irritable bowel syndrome (IBS-D). However, the factors causing excessive BA excretion remains unclear. Given the importance of gut microbiota in BA metabolism, we hypothesized that gut dysbiosis might contribute to excessive BA excretion in IBS-D. <h4>Design</h4> Metabolomic a...

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Literature Corpus work: dcf6842b-a5c3-5ff2-8e24-705ed86372b9
DOI: 10.1101/630350

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