Article

Capturing biological interactions improves predictive ability of complex traits via epistatic model

2024-04-15

Abstract excerpt

<title>Abstract</title> <p>Recent studies have emphasized the significance of epistatic effects in unraveling the underlying genetic architectures of complex traits. However, the rich landscape of biological interactions is often disregarded when statistically modeling epistatic effects for the purpose of dissecting and predicting complex traits/diseases. In this study, we utilize KEGG pathways as carriers of bio...

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Literature Corpus work: 69785557-f336-506d-8c7b-75f3f4a62935
DOI: 10.21203/rs.3.rs-4069883/v1

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