Article
Epigenetic reprogramming induced by Acetyl-CoA and SAM depletion is an evolutionarily-ancient path to malignant growth
2024-12-13
Abstract excerpt
Despite the vast diversity of life forms and living histories, it appears that all branches of Metazoa face the challenge of tumor growth. Contrary to human tumors, which take years to form, tumors in short-living species can arise within days without accumulating multiple mutations, raising the question whether the paths to tumorigenesis in diverse species have any commonalities. In a fly tumor model caused by lo...
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Identifiers and source
- Literature Corpus work
- 69412cfe-7dc2-57b3-88e3-19e98da2c6dd
- DOI
- 10.1101/2024.12.10.627655