Article
The metabolic alterations of cancer cells.
Methods in enzymology - 1 Jan 2014
Sciacovelli Marco, Gaude Edoardo, Hilvo Mika, Frezza Christian
Abstract excerpt
Cancer cells exhibit profound metabolic alterations, allowing them to fulfill the metabolic needs that come with increased proliferation and additional facets of malignancy. Such a metabolic transformation is orchestrated by the genetic changes that drive tumorigenesis, that is, the activation of oncogenes and/or the loss of oncosuppressor genes, and further shaped by environmental cues, such as oxygen...
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