In vivo Reprogramming of Cancer Metabolism by MYC

Abstract excerpt

The past few decades have welcomed tremendous advancements towards understanding the functional significance of altered metabolism during tumorigenesis. However, many conclusions drawn from studies of cancer cells in a dish (i.e. in vitro) have been put into question as multiple lines of evidence have demonstrated that the metabolism of cells can differ significantly from that of primary tumors (in vivo). This...

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