Article

The Tip60/Ep400 chromatin remodeling complex impacts basic cellular functions in cranial neural crest-derived tissue during early orofacial development

2022-12-22

Abstract excerpt

The cranial neural crest plays a fundamental role in orofacial development and morphogenesis. Accordingly, mutations with impact on the cranial neural crest and its development lead to orofacial malformations such as cleft lip and palate. As a pluripotent and dynamic cell population, the cranial neural crest undergoes vast transcriptional and epigenomic alterations throughout the formation of facial structures poi...

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Literature Corpus work: 69025bb8-77ab-59d6-bf27-bee1850a5edb
DOI: 10.1101/2022.12.21.521531

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