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Article

A new perspective on idiopathic pulmonary fibrosis research: From multi-dimensional mechanistic exploration to advances in precision therapy.

Respiratory medicine - 1 Jan 2026

Zhang Shi-Ming, Huang Mei-Zhen, Wang Yi-Wen, Wang Xiao-Fei, Ding Yan, Li Jia-Min, Zou Xiao-Mei, Ma Cheng-Yao

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease characterised by irreversible fibrotic remodelling and a poor prognosis. The typical survival rate is 3-5 years after diagnosis. Although considerable progress has been made in understanding its underlying biology, early detection remains difficult and available treatments provide only limited benefit. Current evidence points...

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PMID: 42251910
DOI: 10.1016/j.rmed.2026.108946

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