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IL-8 Instructs Macrophage Identity in Lateral Ventricle Contacting Glioblastoma

2024-03-30

Abstract excerpt

Adult IDH-wildtype glioblastoma (GBM) is a highly aggressive brain tumor with no established immunotherapy or targeted therapy. Recently, CD32 + HLA-DR hi macrophages were discovered to have displaced resident microglia in GBM tumors that contact the lateral ventricle stem cell niche. Since these lateral ventricle contacting GBM tumors have especially poor outcomes, identifying the origin and role of these CD32...

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Literature Corpus work
68f151f4-5cc5-5bb9-bcc3-63183d0c7d0d
DOI
10.1101/2024.03.29.587030
Open publication

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IL-8 Instructs Macrophage Identity in Lateral Ventricle Contacting GlioblastomaDOI 10.1101/2024.03.29.587030
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