Article

TGF-β signalling regulates the balance between protective and regulatory CD4⁺ T cell responses in visceral leishmaniasis

2026-08-07

Abstract excerpt

Visceral leishmaniasis (VL) is a potentially fatal parasitic disease in which effective immunity requires sufficient inflammation to control parasites while limiting immune-mediated tissue damage. Transforming growth factor-beta (TGFβ) is an important regulator of immune homeostasis and has been implicated in VL, but how it directly controls parasite-specific CD4⁺ T cell responses remains poorly understood. We use...

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Literature Corpus work: 68c4dbed-3556-5e46-953b-2a9bc67657ee
DOI: 10.64898/2026.08.03.742418

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