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Article

TRANSFORMING GROWTH FACTOR-β REGULATION OF IMMUNE RESPONSES

8 Nov 2005

Abstract excerpt

Transforming growth factor-beta (TGF-beta) is a potent regulatory cytokine with diverse effects on hemopoietic cells. The pivotal function of TGF-beta in the immune system is to maintain tolerance via the regulation of lymphocyte proliferation, differentiation, and survival. In addition, TGF-beta controls the initiation and resolution of inflammatory responses through the regulation of chemotaxis, activation, and...

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Identifiers

PMID: 16551245
DOI: 10.1146/annurev.immunol.24.021605.090737

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