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REGULATION OF IMMUNE RESPONSES BY TGF-β

1 Apr 1998

Abstract excerpt

The transforming growth factor beta (TGF-beta) family of proteins are a set of pleiotropic secreted signaling molecules with unique and potent immunoregulatory properties. TGF-beta 1 is produced by every leukocyte lineage, including lymphocytes, macrophages, and dendritic cells, and its expression serves in both autocrine and paracrine modes to control the differentiation, proliferation, and state of activation...

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PMID: 9597127
DOI: 10.1146/annurev.immunol.16.1.137

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