Article

Dietary Restriction Fails to Extend Lifespan of <i>Drosophila</i> Model of Werner Syndrome

2023-09-22

Abstract excerpt

Werner syndrome (WS) is a rare genetic disease in humans, caused by mutations in the WRN gene that encodes a protein containing helicase and exonuclease domains. WS is characterized by symptoms of accelerated aging in multiple tissues and organs, involving increased risk of cancer, heart failure, and metabolic dysfunction. These conditions ultimately lead to the premature mortality of patients with WS. In this st...

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Literature Corpus work: 689e2a86-122f-548e-b147-bb91d4575a29
DOI: 10.1101/2023.09.20.558691

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