Article

Unsupervised learning reveals landscape of local structural motifs across protein classes

2023-12-05

Abstract excerpt

<h4>ABSTRACT</h4> Proteins are known to share similarities in local regions of 3D structure even across disparate global folds. Such correspondences can help to shed light on functional relationships between proteins and identify conserved local structural features that lead to function. Self-supervised deep learning on large protein structure datasets has produced high-fidelity representations of local structura...

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Literature Corpus work: 6875652d-e80e-598a-8719-9ae4a9671572
DOI: 10.1101/2023.12.04.569990

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