Article

Genome-scale annotation of protein binding sites via language model and geometric deep learning

2023-11-05

Abstract excerpt

Revealing protein binding sites with other molecules, such as nucleic acids, peptides, or small ligands, sheds light on disease mechanism elucidation and novel drug design. With the explosive growth of proteins in sequence databases, how to accurately and efficiently identify these binding sites from sequences becomes essential. However, current methods mostly rely on expensive multiple sequence alignments or expe...

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Literature Corpus work: 3379c54e-d528-5c8a-8420-c93b9ef54e3a
DOI: 10.1101/2023.11.02.565344

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