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Delta variant with P681R critical mutation revealed by ultra-large atomic-scale <i>ab initio</i> simulation: Implications for the fundamentals of biomolecular interactions

2021-12-03

Abstract excerpt

<h4>ABSTRACT</h4> SARS-CoV-2 Delta variant is emerging as a globally dominant strain. Its rapid spread and high infection rate are attributed to a mutation in the spike protein of SARS-CoV-2 allowing the virus to invade human cells much faster and with increased efficiency. Particularly, an especially dangerous mutation P681R close to the furin cleavage site has been identified as responsible for increasing the i...

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Literature Corpus work: 6833bc8a-a1a8-5249-939c-bedb6b915f78
DOI: 10.1101/2021.12.01.470802

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