Article

The SARS-CoV-2 Spike Variant D614G Favors an Open Conformational State

2020-07-26

Abstract excerpt

<h4>Summary</h4> The COVID-19 pandemic underwent a rapid transition with the emergence of a SARS-CoV-2 variant that carried the amino acid substitution D614G in the Spike protein that became globally prevalent. The G-form is both more infectious in vitro and associated with increased viral loads in infected people. To gain insight into the mechanism underlying these distinctive characteristics, we employed multi...

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Literature Corpus work: ffe36dd2-8c16-52d8-811f-8b9805261790
DOI: 10.1101/2020.07.26.219741

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