Article
Single-oocyte proteome-transcriptome co-profiling reveals a role of dysregulated lactate metabolism in oocyte aging
2025-05-09
Abstract excerpt
<title>Abstract</title> <p>The declined oocyte quality with age is a major risk factor for female infertility. Although transcriptomic changes have been examined in aged oocytes, the proteomic landscape, which reflects the primary functional executors of genes, and factors shaping the landscape, remains largely unexplored. This gap limits our understanding of molecular features driving oocyte aging. To address th...
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Identifiers and source
- Literature Corpus work
- 683219bc-a96f-5fcc-8e3c-cf0ff068c819
- DOI
- 10.21203/rs.3.rs-6309099/v1