Article

Elamipretide reverses female fertility decline during reproductive aging via regulating VEGF in oocytes

2026-05-31

Abstract excerpt

Aging is one of the primary drivers for the decline of female fertility, and oocyte quality is the main cause for ovary aging, which is related with infertility. Although some effective anti-aging natural components have been reported, highly efficient strategies for reversing ovary aging remain lacking. In this study, we reported that peptide elamipretide reserved ovary function for female fertility during matern...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1c6bebd5-f7d2-58d2-971a-7288d0f560be
DOI: 10.64898/2026.05.27.728315

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Elamipretide reverses female fertility decline during reproductive aging via regulating VEGF in oocytesDOI 10.64898/2026.05.27.728315Read

Oocyte aging underlies female reproductive aging: biological mechanisms and therapeutic strategiesSemantic proximity Read

Oocyte aging: cellular and molecular changes, developmental potential and reversal possibilitySemantic proximity Read

Cell-Free Fat Extract Improves Ovarian Function and Fertility in Mice With Advanced AgeSemantic proximity Read

Single-oocyte proteome-transcriptome co-profiling reveals a role of dysregulated lactate metabolism in oocyte agingSemantic proximity Read

Oocyte quality and agingSemantic proximity Read

Age-associated changes in cumulus cells and follicular fluid: the local oocyte microenvironment as a determinant of gamete qualitySemantic proximity Read

C-type natriuretic peptide improves maternally aged oocytes quality by inhibiting excessive PINK1/Parkin-mediated mitophagySemantic proximity Read

C-type natriuretic peptide improves maternally aged oocytes quality by inhibiting excessive PINK1/Parkin-mediated mitophagySemantic proximity Read

C-type natriuretic peptide improves maternally aged oocytes quality by inhibiting excessive PINK1/Parkin-mediated mitophagySemantic proximity Read

Fisetin Delays Postovulatory Oocyte Aging by Regulating Oxidative Stress and Mitochondrial Function through Sirt1 PathwaySemantic proximity Read

α‐ketoglutarate delays age‐related fertility decline in mammalsSemantic proximity Read

“All-in-one” Single-Cell Proteomic Analysis of Protein Alterations in Human Oocytes Undergoing in Vitro AgingSemantic proximity Read