Article
C-type natriuretic peptide improves maternally aged oocytes quality by inhibiting excessive PINK1/Parkin-mediated mitophagy
2023-05-09
Abstract excerpt
The overall oocyte quality declines with ageing, and this effect is strongly associated with a higher reactive oxygen species (ROS) level and the resultant oxidative damage. C-type natriuretic peptide (CNP) is a well-characterized physiological meiotic inhibitor that has been successfully used to improve immature oocyte quality during in vitro maturation (IVM). However, the underlying roles of CNP in maternally ag...
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Identifiers and source
- Literature Corpus work
- 1de96627-36b1-5fee-8bfb-2eafaaca8571
- DOI
- 10.1101/2023.05.08.538611
