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Rejuvenation of aged oocyte through exposure to young follicular microenvironment

2024-03-13

Abstract excerpt

Reproductive aging is a major cause of fertility decline, attributed to decreased oocyte quantity and competence. Follicular somatic cells play crucial roles in the growth and development of the oocyte by providing nutrients and regulatory factors. Here we investigated how oocyte quality is affected by its somatic cell environment by creating chimeric follicles, whereby an oocyte from one follicle was transplanted...

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Literature Corpus work
63cce7a6-4571-5a19-b797-ec41cde95d35
DOI
10.1101/2024.03.11.584343
Open publication

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Rejuvenation of aged oocyte through exposure to young follicular microenvironmentDOI 10.1101/2024.03.11.584343
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