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Establishment of an efficient reverse genetic system of Mumps virus S79 from cloned DNA

28 Aug 2019

Abstract excerpt

Mumps is a common type of respiratory infectious disease caused by mumps virus (MuV), and can be effectively prevented by vaccination. In this study, a reverse genetic system of MuV that can facilitate the rational design of safer, more efficient mumps vaccine candidates is established. MuV-S79 cDNA clone was assembled into a full-length plasmid by means of the GeneArt™ High-Order Genetic Assembly System, and was...

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PMID: 31456156
DOI: 10.1007/s12519-019-00286-8

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