Article

Single-cell repertoire tracing identifies rituximab refractory B cells during myasthenia gravis relapses

2019-11-14

Abstract excerpt

Rituximab, a B cell-depleting therapy, is indicated for treating a growing number of autoantibody-mediated autoimmune disorders. However, relapses can occur after treatment and autoantibody-producing B cell subsets may be found during relapses. It is not understood if these autoantibody-producing B cell subsets emerge from the failed depletion of pre-existing B cells or are re-generated de novo . To further defin...

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Literature Corpus work: 67f0983d-278c-5e0b-a227-a432ed0937ee
DOI: 10.1101/840389

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