Article

Distribution and Temporal Changes of Autoantibody-Mediated Pathogenic Mechanisms Among Acetylcholine Receptor-Positive Myasthenia Gravis Patients

2024-08-28

Abstract excerpt

<h4>Objective</h4> Given that acetylcholine receptor-positive (AChR+) myasthenia gravis (MG) is mediated by AChR- specific autoantibodies, the emergence of new therapeutics underscores the importance of investigating AChR-specific autoantibody repertoire. This study aimed to assess the distribution of AChR-specific autoantibody isotypes, IgG subclasses, and the pathogenic mechanisms they mediate in AChR+ MG patien...

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Literature Corpus work: 4247860a-6a96-5967-92bf-eec5d3534160
DOI: 10.1101/2024.08.28.24312367

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