Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotype, Severity, and Therapy of Patients With LRP4 Antibody-Associated Myasthenia Gravis in the German Myasthenia Gravis Registry.

Neurology - 11 Aug 2026

Preßler Hannah, Stascheit Frauke, Aigner Annette, Doksani Paolo, Dusemund Carla, Gerischer Lea M, Herdick Meret, Hoffmann Sarah, Lehnerer Sophie, Stein Maike, Blaes Franz, Hagenacker Tim, Lünemann Jan D, Ruck Tobias, Schroeter Michael, Schubert Charlotte, Meisel Andreas, Mergenthaler Philipp

Abstract excerpt

OBJECTIVES: Lipoprotein receptor-related protein 4 antibody-positive myasthenia gravis (LRP4-Ab-positive MG) is a rare serologic subgroup with poorly defined clinical phenotype. This study investigated demographics, clinical features, treatments, and disease burden of LRP4-Ab-positive MG against other antibody-defined subgroups. METHODS: Patients from the prospective longitudinal German MG registry tested for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies
Share to Germany

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to LDL-Receptor Related Proteins

Share to Longitudinal Studies

Share to Myasthenia Gravis

Share to Receptor Protein-Tyrosine Kinases

Share to Receptors, Cholinergic

Share to Registries

Source

Identifiers

PMID: 42407020
DOI: 10.1212/WNL.0000000000218308

Genes

LRP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotype, Severity, and Therapy of Patients With LRP4 Antibody-Associated Myasthenia Gravis in the German Myasthenia Gravis Registry.PMID 42407020Read ↗

Towards personalized management of myasthenia gravis phenotypes: From the role of multi-omics to the emerging biomarkers and therapeutic targets.Semantic proximity Read ↗

Spotlight on MuSK Positive Myasthenia Gravis: Clinical Characteristics, Treatment and OutcomesSemantic proximity Read ↗

Distribution and Temporal Changes of Autoantibody-Mediated Pathogenic Mechanisms Among Acetylcholine Receptor-Positive Myasthenia Gravis PatientsSemantic proximity Read ↗

Circulating miRNAs as Potential Biomarkers in Myasthenia Gravis: Tools for Personalized MedicineSemantic proximity Read ↗

A Retrospective Longitudinal Cohort Study of The Clinical Burden in Myasthenia GravisSemantic proximity Read ↗

Clinical characteristics and outcome of treatment-refractory myasthenia gravis -a retrospective studySemantic proximity Read ↗

Different characteristic phenotypes according to antibody in myasthenia gravis.Semantic proximity Read ↗

Myasthenia gravis: from autoantibodies to therapy.Semantic proximity Read ↗

Prevalence, clinical features and treatment outcomes of patients with myasthenia gravis positive for antibodies to muscle-specific kinase in Thailand.Semantic proximity Read ↗

Diagnostic Performance of ELISA and RIA in AChR Antibody Testing for Myasthenia Gravis: A Real- World Cohort StudySemantic proximity Read ↗

A unique subphenotype of myasthenia gravis.Semantic proximity Read ↗

Reemergence of pathogenic, autoantibody-producing B cell clones in myasthenia gravis following B cell depletion therapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.