Article

Curtailed phase II binary outcome trials and adaptive multi-outcome trials

2021-01-01

Abstract excerpt

Phase II clinical trials are a critical aspect of the drug development process. With drug development costs ever increasing, novel designs that can improve the efficiency of phase II trials are extremely valuable. Phase II clinical trials for cancer treatments often measure a binary outcome. The final trial decision is generally to continue or cease development. When this decision is based solely on the result of...

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Literature Corpus work: 67c79cea-86f3-57ae-b361-98a8a12252b6
DOI: 10.17863/cam.72218

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