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Article

Cerebral organoid model reveals excessive proliferation of human caudal late interneuron progenitors in Tuberous Sclerosis Complex

2020-02-27

Abstract excerpt

<h4>Summary</h4> Although the intricate and prolonged development of the human brain critically distinguishes it from other mammals 1 , our current understanding of neurodevelopmental diseases is largely based on work using animal models. Recent studies revealed that neural progenitors in the human brain are profoundly different from those found in rodent animal models 2–5 . Moreover, post-mortem studies reveal...

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Literature Corpus work
67b31ce1-655b-510e-bcf2-d54c4c116c17
DOI
10.1101/2020.02.27.967802
Open publication

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Cerebral organoid model reveals excessive proliferation of human caudal late interneuron progenitors in Tuberous Sclerosis ComplexDOI 10.1101/2020.02.27.967802
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