Article

Antipsychotic-induced epigenomic reorganization in frontal cortex of individuals with schizophrenia

2021-07-16

Abstract excerpt

Genome-wide association studies have revealed >270 loci associated with schizophrenia risk, yet these genetic factors do not seem to be sufficient to fully explain the molecular determinants behind this psychiatric condition. Epigenetic marks such as post-translational histone modifications remain largely plastic during development and adulthood, allowing a dynamic impact of environmental factors, including antips...

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Literature Corpus work: 67a9db01-0e6a-5fb3-8a4c-3a9ffa404d12
DOI: 10.1101/2021.07.14.452426

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