Clinical actionability in gliomas revealed by real-world next-generation sequencing: a multicentric study

Abstract excerpt

<title>Abstract</title> <p>Treatment options for patients with gliomas remain limited, and prognosis is generally poor. While next-generation sequencing (NGS) is increasingly used to stratify glioma patients and guide therapy, its implementation in routine clinical practice remains variable. We conducted a multicenter retrospective study across seven Spanish hospitals to evaluate the clinical utility of NGS in gl...

Topics

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• Brain Neoplasms
• DNA Copy Number Variations
• Glioblastoma
• Glioma
• High-Throughput Nucleotide Sequencing
• Isocitrate Dehydrogenase
• Mutation
• World Health Organization

Identifiers and source

Literature Corpus work

67914343-02d9-5f74-beff-64fde11a3834

DOI

10.21203/rs.3.rs-6903120/v1